解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
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公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
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毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Barley geneticists are currently using association genetics to identify and fine map traits directly in elite plant breeding material. This has been made possible by the development of a highly parallel SNP assay platform that provides sufficient marker density for genome-wide scans and linkage disequilibrium-led gene...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.12.007
更新日期:2009-04-01 00:00:00
abstract::Plants are sedentary, and so have unavoidably close contact with agents that target their genome integrity. To sense and react to these threats, plants have evolved DNA stress checkpoint mechanisms that arrest the cell cycle and activate the DNA repair machinery to preserve the genome content. Although the pathways th...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.09.012
更新日期:2009-02-01 00:00:00
abstract::Plants have acquired the ability for organized multicellular development independent from animals. Because of this, they represent an independent example in nature for the development of coordinated, complex cell polarity from the simple polarity found in unicellular eukaryotes. Plants display a striking array of pola...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.09.009
更新日期:2009-02-01 00:00:00
abstract::Molecular cloning of mutations affecting the morphology of plant leaves has proven to be useful for the causal analysis of leaf development. Studies of leaf mutants have produced a wealth of biologically meaningful information on the genes that participate in leaf initiation, leaf polarity specification and maintenanc...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.11.001
更新日期:2009-02-01 00:00:00
abstract::Membrane specialization through lateral compartmentalization is pivotal to the development of organisms and their response to environmental signals. The membrane raft hypothesis is lively discussed as a concept for domain formation. In recent years plant scientists have begun to critically assess the membrane raft hyp...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.07.002
更新日期:2008-12-01 00:00:00
abstract::In higher plants, one of the most striking effects of light at the cellular level is the formation of phytochrome nuclear bodies (PNBs). In Arabidopsis, two types of PNBs have been described: a transient type of PNBs (tPNBs), containing both phytochrome A and phytochrome B, observed during the dark-to-light transition...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.06.012
更新日期:2008-10-01 00:00:00
abstract::The lipid-derived hormone jasmonate (JA) regulates diverse aspects of plant immunity and development. Among the central components of the JA signaling cascade are the E3 ubiquitin ligase SCFCOI1 and Jasmonate ZIM-domain (JAZ) proteins that repress transcription of JA-responsive genes. Recent studies provide evidence t...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.05.004
更新日期:2008-08-01 00:00:00
abstract::Phytopathogenic bacteria suppress plant innate immunity and promote pathogenesis by injecting proteins called type III effectors into plant cells using a type III protein secretion system. These type III effectors use at least three strategies to alter host responses. One strategy is to alter host protein turnover, ei...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.06.007
更新日期:2008-08-01 00:00:00
abstract::Progress has been made toward understanding the biosynthesis and modifications of the cellulose and the hemicellulose/pectin matrix of woody cell walls (and hence wood properties) by identifying 1600 carbohydrate active enzymes (CAZYmes) in Populus, and pinpointing key candidates involved in various developmental stag...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.03.003
更新日期:2008-06-01 00:00:00
abstract::Cellulose is the world's most abundant biopolymer and a key structural component of the plant cell wall. Cellulose is comprised of hydrogen-bonded beta-1,4-linked glucan chains that are synthesized at the plasma membrane by large cellulose synthase (CESA) complexes. Recent advances in visualization of fluorescently la...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.03.007
更新日期:2008-06-01 00:00:00
abstract::Active research in rice genetics aided by full-genome sequence has generated results to address multiple problems caused by biotic and abiotic stresses. The main challenges are achieving stability of resistance against variable biological agents and defining the genetic basis of traits influenced strongly by genotypex...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.12.005
更新日期:2008-04-01 00:00:00
abstract::Conventional breeding for drought-prone environments (DPE) has been complemented by using exotic germplasm to extend crop gene pools and physiological approaches that consider water uptake (WU), water-use efficiency (WUE), and harvest index (HI) as drivers of yield. Drivers are associated with proxy genetic markers, s...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.02.005
更新日期:2008-04-01 00:00:00
abstract::High-throughput DNA sequencing and genotyping technologies have enabled a new generation of research in plant genetics where combined quantitative and population genetic approaches can be used to better understand the relationship between naturally occurring genotypic and phenotypic diversity. Forest trees are highly ...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.12.004
更新日期:2008-04-01 00:00:00
abstract::Completion of the genomic sequencing of rice has enhanced the discovery of new genes. Wild rice relatives are good sources for extending the genetic variation of cultivated rice. Reproductive barriers are commonly found in distant crosses of rice and are attracting attention. The combination of genetic analyses and mo...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.01.008
更新日期:2008-04-01 00:00:00
abstract::Plant hormones are tightly regulated in response to environmental and developmental signals. It has long been speculated that biosynthesis of hormones occurs broadly in plant organs and that intricate, spatiotemporal regulation of hormones in developing organ primordia is achieved through transport and signal percepti...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.10.008
更新日期:2008-02-01 00:00:00
abstract::In contrast to animals, gametes in plants form a separate haploid generation, the gametophyte. The female gametophyte of flowering plants consists of just four different cell types that play distinct roles in the reproductive process. Differentiation of the distinct cell fates is tightly controlled and appears to foll...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.07.011
更新日期:2007-12-01 00:00:00
abstract::Stem cells exist in specific locations called niches, where extracellular signals maintain stem cell division and prevent differentiation. In plants, the best characterised niches are within the shoot and root meristems. Networks of regulatory genes and intercellular signals maintain meristem structure in spite of con...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.07.001
更新日期:2007-12-01 00:00:00
abstract::Phytohormone gibberellins (GA) are a large family of tetracyclic diterpenoids and play the important roles in modulation of plant growth and development throughout the plant life cycle. GA depresses its signaling by the GA-promoted destabilization of the DELLA protein growth repressors via 26S proteasome pathway. Rece...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.08.011
更新日期:2007-10-01 00:00:00
abstract::Salicylic acid (SA) is synthesised by plants in response to challenge by a diverse range of phytopathogens and is essential to the establishment of both local and systemic-acquired resistance (SAR). SA application induces accumulation of pathogenesis-related (PR) proteins. Mutations leading to either reduced SA produc...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.08.008
更新日期:2007-10-01 00:00:00
abstract::Many aphids are major agricultural pests because of their unparalleled reproductive capacity and their ability to manipulate host plant physiology. Aphid population growth and its impact on plant fitness are strongly influenced by interactions with other organisms, including plant pathogens, endophytes, aphid endosymb...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.06.004
更新日期:2007-08-01 00:00:00
abstract::Plants must adapt to drought stress to survive. The phytohormone abscisic acid (ABA) is produced under drought stress conditions and is essential for the response to drought stress. The ABA level plays an important role in the response, and several enzymes for ABA biosynthesis and catabolism have been identified. Phys...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.04.014
更新日期:2007-06-01 00:00:00
abstract::Suberized cell walls form physiologically important plant-environment interfaces because they act as barriers that limit water and nutrient transport and protect plants from invasion by pathogens. Plants respond to environmental stimuli by modifying the degree of suberization in root cell walls. Salt stress or drought...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.04.004
更新日期:2007-06-01 00:00:00
abstract::Chlamydomonas has traditionally been exploited as an organism that is associated with sophisticated physiological, genetic and molecular analyses, all of which have been used to elucidate several biological processes, especially photosynthesis and flagella function and assembly. Recently, the genomics of Chlamydomonas...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.01.012
更新日期:2007-04-01 00:00:00
abstract::Forest trees in general are out-crossing, long-lived, and at early stages of domestication. Molecular evolution at neutral sites is very slow because of the long generation times. Transferring information between closely related conifer species is facilitated by high sequence similarity. At the nucleotide level, trees...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.01.011
更新日期:2007-04-01 00:00:00
abstract::Variation in grass architecture profoundly affects light capture, competition, and reproductive success, and is responsive to environmental factors such as crowding and nutrient limitation. Recent work in both model and crop systems has uncovered many aspects of the genetic control of branching, including conservation...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.11.015
更新日期:2007-02-01 00:00:00
abstract::The functions of mitochondria and chloroplasts rely on thousands of proteins, mostly imported from the cytosol through specialized import channels. Neither the detailed import mechanisms nor the identities of all targeted proteins are known. Recent surprises include unexpected results concerning import receptors, unex...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.09.002
更新日期:2006-12-01 00:00:00
abstract::The ubiquitin proteasome system is a key regulator of many biological processes in all eukaryotes. This mechanism employs several types of enzymes, the most important of which are the ubiquitin E3 ligases that catalyse the attachment of polyubiquitin chains to target proteins for their subsequent degradation by the 26...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.09.003
更新日期:2006-12-01 00:00:00
abstract::Transcription factors (TFs) are a group of proteins that control cellular processes by regulating the expression of downstream target genes. Recent progress has been made in the cloning and characterization of Arabidopsis TFs on the genome scale, especially on the cloning of open reading frames (ORFs), sequence analys...
journal_title:Current opinion in plant biology
pub_type: 杂志文章
doi:10.1016/j.pbi.2006.07.005
更新日期:2006-10-01 00:00:00
abstract::The phytohormones gibberellin (GA) and abscisic acid (ABA) play essential and often antagonistic roles in regulating plant growth, development and stress responses. The long-awaited identification of receptors for both GA and ABA has shed light upon the initial events that surround the perception of these two phytohor...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.07.007
更新日期:2006-10-01 00:00:00
abstract::Symbiosis between a fungus and a plant is a widespread phenomenon in nature. The outcome of such an interaction can vary in a seamless manner from mutualism to parasitism. In most cases, the host plant does not suffer, in fact it often gains an advantage from colonization by a fungus. This benefit is based on a fine-t...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.05.001
更新日期:2006-08-01 00:00:00
abstract::Bacterial pathogens have co-evolved with their hosts in their ongoing quest for advantage in the resulting interaction. These intimate associations have resulted in remarkable adaptations of prokaryotic virulence proteins and their eukaryotic molecular targets. An important strategy used by microbial pathogens of anim...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.05.005
更新日期:2006-08-01 00:00:00
abstract::Innate defense in wild plant populations is an invaluable resource for understanding how sustainable disease control can be achieved in crops through research that is rooted in molecular and evolutionary biology. Much progress has been made from molecular research into pathogen detection and defense induction. Bacteri...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.05.011
更新日期:2006-08-01 00:00:00
abstract::Terpene synthases are the primary enzymes in the formation of low-molecular-weight terpene metabolites. Rapid progress in the biochemical and molecular analysis of terpene synthases has allowed significant investigations of their evolution, structural and mechanistic properties, and regulation. The organization of ter...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.03.014
更新日期:2006-06-01 00:00:00
abstract::In plants, newly synthesized fatty acids are either directly incorporated into glycerolipids in the plastid or exported and assembled into lipids at the endoplasmic reticulum (ER). ER-derived glycerolipids serve as building blocks for extraplastidic membranes. Alternatively, they can return to the plastid where their ...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.03.012
更新日期:2006-06-01 00:00:00
abstract::Medicago truncatula will be among the first plant species to benefit from the completion of a whole-genome sequencing project. For each of these species, Arabidopsis, rice and now poplar and Medicago, annotation, the process of identifying gene structures and defining their functions, is essential for the research com...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.01.004
更新日期:2006-04-01 00:00:00
abstract::With a size approximating that of the human genome, the maize genome is about to become the largest plant genome yet sequenced. Contributing to that size are a whole-genome duplication event and a retrotransposition explosion that produced a large amount of repetitive DNA. This DNA is greatly under-represented in cDNA...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.01.009
更新日期:2006-04-01 00:00:00
abstract::Double fertilization in flowering seed plants requires intercellular signaling events between many interacting partners. The four cell types of the seven-celled female gametophyte communicate with each other to establish and maintain their identity. They secrete signaling molecules to guide the male gametophyte and to...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2005.11.002
更新日期:2006-02-01 00:00:00
abstract::One of the most important demands of multicellularity is the co-ordination of cell proliferation and cell growth to allow the ultimate differentiation of functional organs and tissues. In plants, endogenously and exogenously generated developmental signals hone a basic patterning plan to the demands of a changing envi...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2005.11.007
更新日期:2006-02-01 00:00:00
abstract::Recent advances in the study of plant peroxisomes are shedding new light on the importance of these organelles for plant development, and are revealing similarities and differences in peroxisome protein import pathways between plants, animals and fungi. For example, the import of matrix proteins that carry the PTS1 an...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2005.09.009
更新日期:2005-12-01 00:00:00
abstract::Since plants are sessile they must be able to sense and rapidly respond to changes in ambient temperature. Key aspects of plant development, including the transition to flowering and the circadian clock, have important inputs from ambient temperature. In the model system Arabidopsis thaliana, molecular candidates for ...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2005.07.011
更新日期:2005-10-01 00:00:00